Loneliness and social isolation over a longer period of time would cause depression, or vice versa if I say so, a depressed person would isolate himself or herself from society. It would be a flow of certain chemicals in the brain due to which a person tends to lose enthusiasm and excitement, or the fun of life, All human behavior is a result of some sort of chemical reaction or chemical flow in our brains which triggers our actions of being happy or sad. It surely would impact health.
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